Week 5 Discussion
MP is a 55-year-old woman who presents with complaint of inability to hold urine. She describes incidents where laughing or coughing results in a small to moderate release of urine. She has started wearing Peri Pads to avoid embarrassment.
Past Medical History
Six vaginal deliveries, all to full term
Boniva, 150 mg once a month
Calcium, 500 mg daily
Vitamin D3, one daily
Mother, alive and well; hypertension, type 2 diabetes
Father, deceased; cardiovascular disease, myocardial infarction at age 77
No alcohol intake
Walks 2 miles/day
Vital signs normal
Palpation of uterus suggests enlargement
Liver function: Normal
1. What factors in MP’s history would help support a diagnosis of overactive bladder?
2. The clinician prescribes oxybutynin 10 mg (extended-release). What does MP need to know about this drug?
3. If oxybutynin is ineffective, the clinician could use mirabegron, a beta-3 agonist. What does MP need to know about this new drug?